Teaching Resources

1

interventions

Feldman,W. et al. The Use of Dietary Fiber in the Management of Simple, Childhood, Idiopathic, Recurrent, Abdominal Pain. AJDC 1985; 139:1216-18

No

2

diagnostic tests

Wong, M.L. Case, S.O. Leonidas,J.C. et al. Sonographic Diagnosis of Acute Appendicitis in Children. Journal of Pediatric Surgery 1994;(29)10:1356-1360

Suspected appendicitis 

No

3

guidelines

Working Group of the BAPM and Research Unit of the Royal College of Physicians. Development of audit measure guidelines for good practice in the management of neonatal respiratory distress syndrome. Arch Dis. Child 1992;67: 1221-1227

Management of neonatal RDS

No

4

overviews

Vander Stichele,R.H. et al. Systematic review of clinical efficacy of topical treatments for head lice. BMJ 1995;311: 604-608

School head lice problem 

No

5

prognosis

Nelson,K.B. et al. Prognosis in Children With Febrile Seizures. Pediatrics 1978;(61)5:720-727

Febrile seizures

No

6

clinical decision making

Klebanoff,M.A. Read,J.S. Mills,J.L. Siono PH. The risk of childhood cancer after neonatal exposure to vitamin K. NEJM 1993;329(13):905-908

Vit K admin to newborns 

No

7

harm

Golding,J. Greenwood,R. Birmingham,K. Mott,M. Childhood cancer, intra-muscular vitamin K, and pethidine given during labour. BMJ 1992;305:341-346

Vit K admin to newborns (I) 

No

8

interventions

Klassen,T.P. Feldman,M.E. Watters,L.K. et al. Nebulized budesonide for children with mild-to-moderate croup. NEJM 1994; 331(5)285-289

Management of croup in gen practice 

Yes

9

overviews

Roberts,I. Kramer,M.S. Suissa,S. Does home visiting prevent childhood injury? A systematic review of randomised controlled trials. BMJ 1996; 312:29-33

Purchasing health visitor services 

Yes

10

clinical decision analysis

Kramer,M.S. Tange,S.M. Drummond,K.N. Mills,E.L. Urine testing in young febrile children: A risk-benefit analysis. The Journal of Paediatrics 1994;125:6-13

Risks & benefits of urine testing 

No

11

economic evaluation

Lieu,T.A. Schwartz,J.S. Jaffe,D.M. Fleisher,G.R. Strategies for diagnosis and treatment of children at risk for occult bacteremia: Clinical effectiveness and cost-effectiveness. The Journal of Paediatrics 1991;118(1):21-29

Management of febrile infant 

No

12

diagnostic tests

Moosa,A.A. Quortum,H.A Ibrahim.M.D. Rapid diagnosis of bacterial meningitis with reagent strips. The Lancet 1995; 345:1290-1291

Rapid diagnosis of bacterial meningitis 

No

13

interventions from the consumer perspective

Thornton,J.G. Hewison,J. Lilford,R.J. A Vail. A randomised trial of three methods of giving information about prenatal testing. BMJ 1995; 311:1127-1130

Provision of info about prenatal testing

No

14

diagnostic tests

Winkens,R.A.G. Leffers,P. Trienekesen,T.A.M. Stobberingh,E.E.. The validity of urine examination for urinary tract infections in daily practice. Family Practice 1995; 11(3):290-29

Urine testing

Yes

15

qualitative research

Jones,S. Hopkins,S. Teenage sexual health through the eyes of the teenager: a study using focus groups. Ambulatory Child Health (1997) 3:3-11

Sex education in schools

No

16

prognosis

Holloway,J. S. Outcome in placements for adoption or long term fostering. Archives of Diseases in Childhood 1997; 76:227-230

Soc svcs dilemma about adoption and fostering

No

17

trade off for harms & benefits

Glasziou,P.P. Hayem,M. Treatments for acute otitis media children: antibiotic versus placebo. The cochrane library {database on disk and CDROM}. The Cochrane Collaboration ; Issue 1. Oxford: Update Software; 1997

Treatment of earache

No

18

diagnostic tests

Tubman,T.R.J. Shields,M.D. Craig,B.G. et al. Congenital heart disease in Down's syndrome: two year prospective early screening study. BMJ 1991;302:1425-7

Examination for cardiac defects in newborn babies

Yes

19

qualitative research

Eiser,C. Havermans,T. Eiser,J.R. Parents' attributions about childhood cancer: implications for relationships with medical staff. Child: Care, health and development 1995;21:31-42

Parents' attributions about childhood cancer

No

20

prognosis

Downie,A.B. Mulligan,J. Strafford.R.J et al. Are normal children at a disadvantage? The Wessex growth study. BMJ 1997, 314:97-100

'Short stature'

No

21

harm

Rothman,K.J. Moore,L.L. Singer,M.R. et al. Teratogenicity of High Vitamin A Intake. NEJM 1995;333:21 1369-1373

Vitamin A in pregnancy

No

22

interventions

Madge,P. McColl,J. Paton,J. Impact of nuse-led management training programme in children admitted to hospital with acute asthma: a randomised controlled study. Thorax 1997;52(3):223-228

Nurse-led home asthma management

Yes

23

diagnostic tests

Law,J. Early language screening in City and Hackney: the concurrent validity of a measure designed for use with 2.5 year olds. Child Care Health Dev 1994;20(5):295-308

Purchasing screening for language impairment

No

24

interventions

Timos Valaes, MD§; Claudia Henschke, MD PHD*. Control of Jaundice in Preterm Newborns by an Inhibitor of Bilirubin Production: Studies with Tin-Mesoporphyrin. PEDIATRICS 1994; 93:(1)1-11

Management of Neonatal Jaundice

No

25

interventions

Bower, E. McClellan, D.L. Arney, J. Campbell, M.J. A randomised controlled trial of different intensities of physiotherapy and different goal-setting procedures in 44 children with cerebral palsy. Development Medicine and Child Neurology 1996;38:226-37

Physiotherapy for cerebral palsy

No

26

diagnostic tests

Saavaedra,J.M. Harris,G.D. Song,L. Finberg,L. Capillary Refilling (Skin Turgor) in Assessment of Dehydration. AJDC 1995:145;296-298

Capillary refill

Yes

27

prognosis

Wilson,A.C. Forsyth,S.J. Greene,S.A. et al. Relation of infant diet to child health: seven year follow up of cohort of children in Dundee infant feeding study. BMJ 1998;316:21-25

Relation of infant feeding to childhood health

Yes

28

qualitative research

Callerly,P. Caring for parents of hospitalized children: a hidden area of nursing work.J Adv Nursing 1997;26:992-998

Nursing parental support

No

29

interventions

Connor,E.M. Sperling,R.S, Gebler,R. et al. Reduction of Maternal-Infant Transmission of Human Immunodefiency Virus 1 with Zidovudine Treatment. NEJM 1994; 331(18)1173-1180

Reduction of Maternal-Infant Transmission of HIV Zidovudine

Yes

30

overviews

Lucassen,P.L.B.J. Assendelft,W.J.J. Gubbels,J.W. et al. Effectiveness of treatments for infantile colic: systematic review BMJ 1998;316:1563-9

Infantile colic

Yes

31

interventions

Hawe, P. McKenzie, N. Scurry, R. Randomised controlled trial of the use of a modified postal reminder card on the uptake of measles vaccination. Arch Dis Child 1998;79:136-140

Measles vaccinations and reminder cards

Yes

32

diagnostic tests

Neilson, D. Hollman, A,S. The Ultrasonic Diagnosis of Infantile Hypertrophic Pyloric Stenosis: Technique and Accuracy. Clinical Radiology 1994;49:246-247

Ultrasonic diagnosis

Yes

33

overviews

McIntyre, T.B. Berkey, C.S. King, S.M. et al Dexamethasone as adjunctive therapy in bacterial meningitis: a meta-analysis of randomised clinical trials since 1988. JAMA. 1997 Sep 17;278: 925-31

Dexamethasone

Yes

34

overviews

The Albumin Reviewers (Alderson P, Bunn F. Lefebvre C, Li Wan Po A, Li L, Roberts, I, Schierout G?. Human albumin administration in critically ill patients. The Cochrane Library - 1998 Issue 3

Use of albumin

Yes

35

qualitative research

Kai,J. What worries parents when their preschool children are acutely ill, and why: a qualitative study. BMJ 1996;313:983-986

Introduction of advice/assurance telephone service

No

36

prognosis

Bennett,K.E Haggard,M.P. Behaviour and cognitive outcomes from middle ear disease. Arch Dis Child 1999; 80: 28-35

Middle ear disease and behavioural problems

Yes

37

diagnosis

Mandl KD, Stack AM, Fleisher GR. Incidence of bacteremia in infants and children with fever and petechiae. J of Paediatrics 1997; 131: 398-404

Petechiae and fever

Yes

38

interventions

Wesseldine LJ, McCarthy P, Silverman M. Structured discharge procedure for children admitted to hospital with acute asthma: a randomised controlled trial of nursing practice. Arch Dis Child 1999; 80:110-114

Nurse led asthma education programme

Yes

39

qualitative research

Hoddinott P, Roisin P. Qualitative study of decisions about infant feeding among women in east end of London. BMJ 1999; 318:30-34

Infant feeding

No

40

prognosis

Waters DL, Wilcken B, Irwig L, Van Aperen P, Mellis C, Simpson JM, Brown J, Gaskin KJ. Clinical outcomes of newborn screening for cystic fibrosis. Arch Dis Child Fetal Neonatal Ed 1999; 80: F1-F7

Screening for cystic fibrosis

No

41

harm

Thomas S, Acton C, Nixon J, Battistutta D, Pitt WR, Clark R. 'Effectivemess of bicycle helmets in preventing head injury in children: case-control study.' BMJ 1994; 308:173-176

'Effectiveness of bicycle helmets'

Yes

42

interventions

Uhari M, Kontiokari T, Niemela M. 'A Novel Use of Xylitol Sugar in Preventing Acute Otitis Media.' Pediatrics 1998;102:879-884

Otitis Media

No

43

interventions

Hossain S; Biswas R; Kabir I; Sarker S; Dibley M; Fuchs G; Mahalanabis D. ‘Single Dose Vitamin A Treatment in Acute Shigellosis in Bangladishi Children: Randomised Double Blind Controlled Trial.' BMJ 1998;316:422-426

Vitamin A Treatment in Acute Shigelloisis

No

44

causation (cohort study)

Sigurs N, Bjarnason R, Sigurbergsson F, Kjellman B, Bjorksten B. ‘Asthma and Immunoglobulin E Antibodies After Respiratory Syncytial Virus Bronchiolitis: A Prospective Cohort Study With Matched Controls.' Pediatrics 1995;95:500-505

Respiratory Syncytial Virus

Yes

45

interventions

The Impact-RSV Study Group ‘Palivizumab, a Humanized Respiratory Syncytial Virus Monoclonal Antibody, Reduces Hospitalization From Respiratory Syncytial Virus Infection in High-risk Infants.' Pediatrics 1998; 102: 531-537

Palivizumab reduces hospitalization from RSV

Yes

46

qualitative research

Van Dongen JEWM, Van Zuuren FJ, Verhulst FC. 'Experiences of parents of childhood cancer survivors: a qualitative analysis.' Patient Education and Counselling 1998;34:185-200

Childhood cancer

No

47

prognosis

Goss JA, Shackleton CR, McDiarmid SV, Maggard M, Swenson K, Seu P et al. 'Long-term results of pediatric liver transplantion: an analysis of 569 transplants.' Ann Surg 1998;228:411-420

Liver transplantations

No

48

causation (case control)

Macarthur C, Saunders N, Feldman W, Ipp M, Winders LP, Roberts S et al. 'Helicobacter pylori and childhood recurrent abdomincal pain: community based case-control study.' BMJ 1999;319:822-823

RAP

Yes

49

overview

Griffin S, Ellis S, Fitzgerald BA, Rose J, Egger M. 'Nebulised steroid in the treatment of croup: a systematic review of randomised controlled trials.' Br J Gen Pract 2000;50:135-141

Steroid treatment of croup

Yes

50

interventions

Damoiseaux RA, van Balen FA, Hoes AW, Verheij, de Melker RA. 'Primary care based randomised, double blind trial of amoxicillin versus placebo for acute otitis media in children aged under 2 years.' BMJ 2000;320:350-354

Antibiotic treatment for otitis media

Yes

51

intervention

Crawley J, Waruiru C, Mithwani S, Mwangi I, Watkins W, Ouma D, Winstanley P, Peto T, Marsh K. 'Effect of phenobarital of seizure frequency and mortality in childhood cerebral malaria: a randomised, controlled intervention study.' The Lancet 2000;355:701

Phenobarital in cerebral malaria

No

52

overview

Hodson EM, Knight JF, Willis NS, Craig JC ' Corticosteroid therapy in nephrotic syndrome: a meta analysis of randomised controlled trials' Arch Dis Child 2000;83:45-51

Corticosteroid therapy in nephortic syndrome

Yes

53

diagnosis

Allen MC, Alexander GR. 'Using motor milestones as a multi-step process to screen preterm infants for cerebral palsy' Developmental Medicine & Child Neurology 1997;39:12-16

Using Motor Milestones

Yes

54

interventions

Ubhi T, Bhakta BB, Ives HL, Allgar V, Roussounis SH. 'Randomised double blind placebo controlled trial of the effect of botulinum toxin on walking in cerebral palsy' Arch Dis Child 2000;83:481-487

Cerebral Palsy

Yes

55

prognosis

Feickert HJ, Drommer S, Heyer R 'Severe head injury in children: Impact of Risk Factors on Outcome.' J Trauma 1999;47:33-38

Sever head injury

Yes

56

diagnosis

Tamburlini G, Di Mario S, Schindler Maggi R, Vilarim N, Gove S. 'Evaluation of guidelines for emergency triage assessment and treatment in developing countries' Arch Dis Child 1999;81:478-482

Emergency triage assessment/triage

No

57

risk factors and causation

Hotopf M, Carr S, Mayou R, Wadsworth M, Wessely S. 'Why do children have chronic abdominal pain, and what happens to them when they grow up? Population based cohort study.' BMJ 1998;316:1196-1200

RAP

Yes

58

interventions

Emslie GJ, Rush AJ, Weinberg WA, Kowatch RA, Hughes CW, Carmody T, Rintelmann J. 'A double-blind, randomised, placebo-controlled trial of fluoxetine in children and adolescent with depression.' Arch Gen Psychiatry 1997;54:1031-1037

Treatment of depression in adolescents

Yes

59

diagnosis

Goodman R, Ford T, Simmons H, Gatward R, Meltzer H. Using the Strengths and Difficulties Questionnaire (SDQ) to screen for child psychiatric disorders in a community sample. British Journal of Psychiatry 2000;177:534-539

SDQ

Yes

60

overview

Harrington R, Whittaker J, Shoebridge P, Campbell F. 'Systematic review of efficacy of cognitive behaviour therapies in childhood and adolescent depressive disorder.' BMJ 1998;316:1559-1563

Cognitive Behavioural Therapy

Yes

62

overview

Gilbert R, Augood C, Maclennan S, Logan S. Cisapride for gastro-oesaphageal reflux in children: A systematic review of randomized controlled trials. J Paed Child Health 2000;36:524-529

Management of gastro-oesaphageal reflux

Yes

63

prognosis

Lucas AR, Melton LJ, Crowson CS, O'Fallon WM. 'Long-term Fracture Risk Among Women With Anorexia Nervosa: A Population-Based Cohort Study' Mayo Clin Proc. 1999;74:972-977

Risk of fracture from anorexia

Yes

64

interventions

Conroy RM, Meegan ME, Joyce T, McGuigan K, Barnes J. Solar disninfection of drinking water protects against cholera in children under 6 years of age. Arch Dis Child 2001; 85:293-295

Solar disinfection

Yes

65

diagnosis

Baird G, Charman T, Baron-Cohen S, Cox A, Swettenham J, Wheelwright S, Drew A. 'A screening instrument for autism at 18 months of age: a 6-year follow-up study.' J Am Acad Child Adolesc Psychiatry 2000;39:694-702

Screening for autism disorders

Yes

66

interventions

Diggle L, Deeks J. ‘Effect of needle length on incidence of local reactions to routine immunisation in infants aged 4 months: randomised controlled trial' BMJ 2000;321:931-933

Effect of needle length on incidence of local reactions

Yes

67

diagnosis

Casey BM, McIntire DD, Leveno KJ. 'The Continuing Value of the Apgar Score for the Assessment of Newborn Infants' N Engl J Med 2001;344:467-471

Apgar scores

Yes

68

interventions

Pierce CM, Wade A, Mok Q. 'Heparin-bonded central venous lines reduce thrombotic and infective complications in critically ill children' Intensive Care Med 200026:967-972

Central venous lines

Yes

69

diagnosis

Magdy W, Zaoutis T, Klein JD, Meier FA. 'Performance of a predictive model for streptococcal pharyngitis in children' Arch Pediatr Adolesc Med 2001;155:687-691

Fever and sore throat

Yes

70

prognosis

Bedford H, de Louvois J, Halket S, Peckham C, Hurley R, Harvey D. 'Meningitis in infancy in England and Wales: follow up at age 5 years' BMJ 2001;323:533

Meningitis

No

71

causation

Sood B, Delaney-Black V, Covington C, Nordstom-Klee B, Ager J, Templin T, Janisse J, Martier S, Sokol RJ. 'Prenatal alcohol exposure and childhood behavior at age 6-7 years: 1. Dose-response effect' Pediatrics 2001;108: 1-9

Foetal alcohol syndrome

No

72

interventions

Wood A, Trainor G, Rothwell J, Moore A, Harrington R. 'Randomized trial of group therapy for repeated deliberate self-harm in adolescents' J. Am. Acad. Child Adolesc. Psychiatry 2001,40(11):1246-1253

Self-harm in adolescents

Yes

73

overview

Petrosino A, Turpin-Petrosino C, Buehler J. '"Scared Straight" and other juvenile awareness programs for preventing juvenile delinquency'. (Cochrane Review). IN: The Cochrane Library, Issue 4, 2002. Oxford: Update Software

Juvenile delinquency

Yes

74

overview

D'Souza AL, Rajkumar C, Cooke J, Bulpitt CJ. 'Probiotics in prevention of antibiotic associated diarrhoea: meta-analysis'. BMJ 2002;324:1361-1366

Diarrhoea associated with antibiotic use

Yes

75

diagnosis

Harnden A, Brueggeman A, Sheppard S, White J, Hayward A, Zambon M, Crook D, Mant D. Near patient testing for influenza in children in primary care: comparison with laboratory test. BMJ 2003;326:480

Influenza Near Patient Test

Yes

76

diagnosis

Garcia Pena BM, Mandl KD, Kraus SJ, Fischer AC, Fleisher GR, Lund DP, Taylor GA. Ultrasonography and limited computed tomography in the diagnosis and management of appendicitis in children. JAMA 1999;282:1041-1046

Appendicitis

Yes

77

overview

Schroeder K, Fahey T. Should we advise parents to administer over the counter cough medicines for acute cough? Systematic review of randomised controlled trials. Arch Dis Child 2002;86:170-175

OTC medicines for acute cough

Yes

78

diagnosis

Boutis K, Lomar L, Jaramillo D, Babyn P, Alman B, Snyder B, Mandl KD, Schuh S.. Sensitivity of a clinical examination to predict need for radiography in children with ankle injuries: a prospective study. Lancet;358:2118-2121

Ankle injuries and need for x-rays

Yes

79

causation (case-control)

McKinney PA, Okasha M, Parslow RC, Law GR, Gurney KA, Williams R, Bodansky HJ. Early social mixing and childhood Type 1 diabetes mellitus: a case-control study in Yorkshire, UK. Diabet.Med. 2000;17:236-242

Diabetes and social mixing

No

80

interventions

Hatakka K, Savilahti E, Ponka A, Meurman JH, Poussa T, Nase L, Saxelin M, Korpela R. Effect of long term consumption of probiotic milk on infections in children attending day care centres: double blind, randomised trial. BMJ, 2001;322:1237

Probiotics

Yes

81

overview

Guevara JP, Wolf FM, Grum CM, Clark NM. Effects of educational interventions for self management of asthma in children and adolescents: systematic review and meta-analysis. BMJ. 2003 Jun 14;326(7402):1308-9.

Self management of asthma

Yes

82

overview

Keith J Barrington. The adverse neuro-developmental effects of postnatal steroids in the preterm infant: a systematic review of RCTs.BMC Pediatrics 2001;1:1

Preterm infants and postnatal steroids

Yes

83

diagnosis

Chartrand LJ, Agulnik J, Vanounou T, Russo PA, Baehler P, Seidman EG. Effectiveness of antigliadin antibodies as a screening test for celiac disease in children. CMAJ 1997 Sep 1;157(5):527-33.

Screening for coeliac disease

Yes

84

overview

Kenyon S, Boulvain M, Neilson J. Antibiotics for preterm rupture of membranes (Cochrane Review). In: The Cochrane Library, Issue 2, 2004. Chichester , UK : John Wiley & Sons, Ltd.

Preterm rupture of membranes

Yes